Built for the shift in kidney care.

One of the costliest areas of U.S. healthcare is changing. From the problem to our answer, XKIDNEY, step by step.

Lifesaving, but costly.

Dialysis is lifesaving, but it is one of the most expensive areas of U.S. healthcare. High spending is not translating to patient longevity or quality of life.

808K

Americans living with kidney failure

About 68% on dialysis 1

$52B

Medicare spend on kidney failure

In 2021 1

$130B

Medicare spend on all kidney disease

CKD $77B + kidney failure $52B, 2021 · 37M Americans with CKD 1 2

  1. NIDDK, Kidney Disease Statistics for the United States (USRDS 2023 Annual Data Report)
  2. CDC, Chronic Kidney Disease in the United States

Crashes turn into $30k–$55k in hospital costs.

When care is late or missed, the bill comes later.

ER + transport
$2k–$5k
Complications / readmit
$8k–$15k
Inpatient admission
$20k–$35k
Per crash, total
$30k–$55k

A crash is a sudden deterioration that ends in the ER or hospital. Bar length shows the upper estimate; company estimates.

Tethered to clinicsCare delivery remains tethered to physical clinics: 3× weekly, 4+ hours.
Frequent crashesFrequent crashes in ~60% of patients lead to ER visits and hospital stays, a large share of Medicare ESRD costs.
Capped throughputDialysis throughput is capped by chairs and staffing, not demand.

A paradigm shift toward value-based care.

CMS is moving U.S. kidney care toward value-based care. VBC operators have raised about $2.5B to reduce ICU costs, manage crash dialysis patients and improve planned home starts.

AnalyticsPatient data analytics.
InterventionPreemptive intervention to reduce crashes and expenditure.
Home dialysisHome dialysis adoption.

Structural barriers to home HD adoption.

Despite strong clinical evidence, patients, service providers and VBC providers each face a barrier.

Patients & caregiversCognitive and emotional burdenQuasi-clinician roles for setup and troubleshooting, anxiety about alarms and hypotension, space, noise and supplies, and 4–8 weeks of training.→ Light to move, automated steps, precise fluid removal
Service providersSafety risks remainNo real-time visibility into home treatments, hard to detect deterioration, and growing burden without matching reimbursement.→ Software automation keeps treatment at home stable
VBC providers & payorsLimited scale and cost-efficiencyHome HD cuts total cost of care significantly, but current models limit scale and outcomes measurement.→ Lowest total cost of care

XKIDNEY is a dialysis platform that brings together clinic-grade performance, care oversight and value-based kidney care.

XKIDNEY with blood lines loaded

4–5× smaller and lighter.

At 29 kg, about a quarter of the weight of a typical in-center machine.

Legacy machines
120 kg+
XKIDNEY
29 kg

Bar length shows weight. Legacy figure is a typical in-center hemodialysis machine, from public specifications.

UF accuracy within ±30 mL/h.

Accurate UF helps reduce the risk of hypotension from over-removal, and makes treatment repeatable anywhere.

Emerging HD devices
±100 mL/h
Legacy machines
±40 mL/h
XKIDNEY
±30 mL/h

XKIDNEY figures come from bench tests under standard conditions.

Catching problems before the alarm.

Today no real-time data exists to power AI for dialysis. XKIDNEY collects it during treatment, so AI-driven treatment optimization can make remote dialysis safer.

During treatment · machine

Arterial & venous pressureDialysate pressureUF volume & rateBlood & dialysate flowConductivity & temperatureBlood leak & air detectionContinuous BP

Before & after · patient

Kt/VWeight gainPre-dialysis BUNHematocrit & hemoglobinUnderlying diseaseElectrolytes

Targeting 30% lower overall cost.

Cost per session, counting machine, services, consumables and delivery (target). Made possible by a simpler pump-based design and minimum consumables.

Simpler designPumps balance fluid directly, so the build stays simple.
Minimum consumablesStandard off-the-shelf disposables, no proprietary cartridge.
Small footprintLess to install, store and ship.

Investor inquiries.

Get in touch info@exorenal.com